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1

N -(3-Acyloxy-2-benzylpropyl)- N ‘-[4-(methylsulfonylamino)benzyl]thiourea Analogues: Novel Potent and High Affinity Antagonists and Partial Antagonists of the Vanilloid Receptor

Lee, Jeewoo, Lee, Jiyoun, Kang, Myungshim, Shin, Myoungyoup, Kim, Ji-Min, Kang, Sang-Uk, Lim, Ju-Ok, Choi, Hyun-Kyung, Suh, Young-Ger, Park, Hyeung-Geun, Oh, Uhtaek, Kim, Hee-Doo, Park, Young-Ho, Ha,

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 184 KB

english, 2003

2

Cinchona-based phase-transfer catalysts for asymmetric synthesis

Jew, Sang-sup, Park, Hyeung-geun

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

3

Novel Cinchona-Aminobenzimidazole Bifunctional Organocatalysts

Lei Zhang, Myoung-Mo Lee, Soo-Mi Lee, Jihye Lee, Maosheng Cheng, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Advanced Synthesis & Catalysis

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

4

Highly Enantioselective and Practical Cinchona-Derived Phase-Transfer Catalysts for the Synthesis of α-Amino Acids

Hyeung-geun Park, Byeong-Seon Jeong, Mi-Sook Yoo, Jeong-Hee Lee, Mi-kyoung Park, Yeon-Ju Lee, Mi-Jeong Kim, Sang-sup Jew

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

5

Highly Enantioselective and Practical Cinchona-Derived Phase-Transfer Catalysts for the Synthesis of α-Amino Acids

Hyeung-geun Park, Byeong-Seon Jeong, Mi-Sook Yoo, Jeong-Hee Lee, Mi-kyoung Park, Yeon-Ju Lee, Mi-Jeong Kim, Sang-sup Jew

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

6

Highly Enantioselective Phase-Transfer Catalytic α-Alkylation of α-tert-Butoxycarbonyllactams: Construction of β-Quaternary Chiral Pyrrolidine and Piperidine Systems

Yohan Park, Young Ju Lee, Suckchang Hong, Mi-hyun Kim, Myungmo Lee, Taek-Soo Kim, Jae Kyun Lee, Sang-sup Jew, Hyeung-geun Park

Journal:

Advanced Synthesis & Catalysis

Year:

2011

Language:

english

File:

PDF, 615 KB

english, 2011

7

Highly Enantioselective Phase-Transfer-Catalytic Alkylation of 2-Phenyl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester for the Asymmetric Synthesis of α-Alkyl Serines

Sang-sup Jew, Yeon-Ju Lee, Jihye Lee, Myoung Joo Kang, Byeong-Seon Jeong, Jeong-Hee Lee, Mi-Sook Yoo, Mi-Jeong Kim, Sea-hoon Choi, Jin-Mo Ku, Hyeung-geun Park

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

8

Highly Enantioselective Epoxidation of 2,4-Diarylenones by Using Dimeric Cinchona Phase-Transfer Catalysts: Enhancement of Enantioselectivity by Surfactants

Sang-sup Jew, Jeong-Hee Lee, Byeong-Seon Jeong, Mi-Sook Yoo, Mi-Jeong Kim, Yeon-Ju Lee, Jihye Lee, Sea-hoon Choi, Kyungjae Lee, Myoung Soo Lah, Hyeung-geun Park

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

9

Highly Enantioselective Phase-Transfer-Catalytic Alkylation of 2-Phenyl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester for the Asymmetric Synthesis of α-Alkyl Serines

Sang-sup Jew, Yeon-Ju Lee, Jihye Lee, Myoung Joo Kang, Byeong-Seon Jeong, Jeong-Hee Lee, Mi-Sook Yoo, Mi-Jeong Kim, Sea-hoon Choi, Jin-Mo Ku, Hyeung-geun Park

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

10

Highly Enantioselective Epoxidation of 2,4-Diarylenones by Using Dimeric Cinchona Phase-Transfer Catalysts: Enhancement of Enantioselectivity by Surfactants

Sang-sup Jew, Jeong-Hee Lee, Byeong-Seon Jeong, Mi-Sook Yoo, Mi-Jeong Kim, Yeon-Ju Lee, Jihye Lee, Sea-hoon Choi, Kyungjae Lee, Myoung Soo Lah, Hyeung-geun Park

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

11

ChemInform Abstract: Synthesis and in vitro Cytotoxicity of Hexacyclic Camptothecin Analogues.

Sang-sup Jew, Hee-Jin Kim, Myoung Goo Kim, Eun-Young Roh, Chung Il Hong, Joon-Kyum Kim, Jun-Hee Lee, Heesoon Lee, Hyeung-geun Park

Journal:

Year:

2000

File:

PDF, 33 KB

2000

12

ChemInform Abstract: Structure—Activity Relationship Study of Asiatic Acid Derivatives Against Beta Amyloid (Aβ)-Induced Neurotoxicity.

Sang-sup Jew, Chi-hyoung Yoo, Doo-yeon Lim, Heeman Kim, Inhee Mook-Jung, Min Whan Jung, Heesung Choi, Young-hoon Jung, Heedoo Kim, Hyeung-geun Park

Journal:

Year:

2000

File:

PDF, 32 KB

2000

13

ChemInform Abstract: Practical Regioselective Synthetic Method for (E)-Enol Ether.

Hyeung-geun Park, Dong-Hwa Kim, Mi-Sook Yoo, Mi-kyoung Park, Sang-sup Jew

Journal:

Year:

2000

File:

PDF, 30 KB

2000

14

ChemInform Abstract: Enantioselective Synthetic Method for 3-Hydroxyflavanones: An Approach to (2R,3R)-3′,4′-O-Dimethyltaxifolin (VIIIb).

Sang-sup Jew, Hyun-ah Kim, So-young Bae, Jeong-hoon Kim, Hyeung-geun Park

Journal:

Year:

2000

File:

PDF, 32 KB

2000

15

ChemInform Abstract: Trimeric Cinchona Alkaloid Phase-Transfer Catalyst: α,α′,α′′-Tris[O(9)-allylcinchonidinium]mesitylene Tribromide.

Hyeung-geun Park, Byeong-seon Jeong, Mi-sook Yoo, Mi-kyoung Park, Hoon Huh, Sang-sup Jew

Journal:

Year:

2001

File:

PDF, 32 KB

2001

16

ChemInform Abstract: Synthesis and Application of Dimeric Cinchona Alkaloid Phase-Transfer Catalysts: α,α′-Bis[O(9)-Allylcinchonidinium]-o,m, or p-Xylene Dibromide.

Sang-sup Jew, Byeong-Seon Jeong, Mi-Sook Yoo, Hoon Huh, Hyeung-geun Park

Journal:

Year:

2001

File:

PDF, 33 KB

2001

17

Highly Enantioselective and Practical Cinchona-Derived Phase-Transfer Catalysts for the Synthesis of α-Amino Acids.

Hyeung-geun Park, Byeong-Seon Jeong, Mi-Sook Yoo, Jeong-Hee Lee, Mi-kyoung Park, Yeon-Ju Lee, Mi-Jeong Kim, Sang-sup Jew

Journal:

Year:

2002

File:

PDF, 35 KB

2002

18

An Unusual Electronic Effect of an Aromatic-F in Phase-Transfer Catalysts Derived from Cinchona-Alkaloid.

Sang-sup Jew, Mi-Sook Yoo, Byeong-Seon Jeong, Il Yeong Park, Hyeung-geun Park

Journal:

Year:

2003

File:

PDF, 203 KB

2003

19

Synthesis of N,N′,N′′-Trisubstituted Thiourea Derivatives and Their Antagonist Effect on the Vanilloid Receptor.

Hyeung-geun Park, et al. et al.

Journal:

Year:

2003

File:

PDF, 8 KB

2003

20

Highly Efficient ortho-Fluoro-dimeric Cinchona-Derived Phase-Transfer Catalysts.

Hyeung-geun Park, Byeong-Seon Jeong, Mi-Sook Yoo, Jeong-Hee Lee, Boon-saeng Park, Myoung Goo Kim, Sang-sup Jew

Journal:

Year:

2003

File:

PDF, 109 KB

2003

21

Highly Enantioselective Synthesis of α-Alkyl-alanines via the Catalytic Phase-Transfer Alkylation of 2-Naphthyl Aldimine tert-Butyl Ester by Using O(9)-Allyl-N(1)-2′,3′,4′-trifluorobenzylhydrocinchonidinium Bromide.

Sang-sup Jew, Byeong-Seon Jeong, Jeong-Hee Lee, Mi-Sook Yoo, Yeon-Ju Lee, Boon-saeng Park, Myoung Kim, Hyeung-geun Park

Journal:

Year:

2003

File:

PDF, 160 KB

2003

22

First Asymmetric Total Synthesis of (-)-Antofine by Using an Enantioselective Catalytic Phase Transfer Alkylation.

Sanghee Kim, Jaekwang Lee, Taeho Lee, Hyeung-geun Park, Deukjoon Kim

Journal:

Year:

2003

File:

PDF, 73 KB

2003

23

N-4-Methansulfonamidobenzyl-N′-2-substituted-4-tert-butyl-benzyl Thioureas as Potent Vanilloid Receptor Antagonistic Ligands.

Hyeung-geun Park, et al. et al.

Journal:

Year:

2004

File:

PDF, 130 KB

2004

24

An Unusual Base-Dependent α-Alkylation and β-Elimination of tert-Butyl 2-Phenyl-2-oxazoline-4-carboxylate: Practical Synthesis of (.+-.)-α-Alkylserines and tert-Butyl Benzamidoacrylate.

Hyeung-geun Park, Jihye Lee, Myoung Joo Kang, Yeon-Ju Lee, Byeong-Seon Jeong, Jeong-Hee Lee, Mi-Sook Yoo, Mi-Jeong Kim, Sea-hoon Choi, Sang-sup Jew

Journal:

Year:

2004

File:

PDF, 104 KB

2004

25

Evidence of the Electronic Factor for the Highly Enantioselective Catalytic Efficiency of Cinchona-Derived Phase-Transfer Catalysts.

Mi-Sook Yoo, Byeong-Seon Jeong, Jeong-Hee Lee, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2005

File:

PDF, 34 KB

2005

26

Highly Enantioselective Synthesis of (R)-α-Alkylserines via Phase-Transfer Catalytic Alkylation of o-Biphenyl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester Using Cinchona-Derived Catalysts.

Yeon-Ju Lee, Jihye Lee, Mi-Jeong Kim, Taek-Soo Kim, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2005

File:

PDF, 21 KB

2005

27

Highly Enantioselective Synthesis of (2S)-α-(Hydroxymethyl)-glutamic Acid by the Catalytic Michael Addition of 2-Naphthalen-1-yl-2-oxazoline-4-carboxylic Acid tert-Butyl Ester.

Yeon-Ju Lee, Jihye Lee, Mi-Jeong Kim, Byeong-Seon Jeong, Jeong-Hee Lee, Taek-Soo Kim, Jihoon Lee, Jin-Mo Ku, Sang-sup Jew, Hyeung-geun Park

Journal:

Year:

2005

File:

PDF, 25 KB

2005

28

ChemInform Abstract: The Highly Enantioselective Phase-Transfer Catalytic Mono-Alkylation of Malonamic Esters.

Mi-hyun Kim, Sea-hoon Choi, Yeon-Ju Lee, Jihye Lee, Keepyung Nahm, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2009

File:

PDF, 54 KB

2009

29

ChemInform Abstract: Enantioselective Synthesis of (R)-α-Alkylhomoserines and (R)-α-Alkylhomocysteines via Phase-Transfer Catalytic Alkylation.

Taek-Soo Kim, Yeon-Ju Lee, Kyoungyim Lee, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2009

File:

PDF, 41 KB

2009

30

ChemInform Abstract: Highly Enantioselective Synthesis of (S)-α-Alkyl-α,β-diaminopropionic Acids via Asymmetric Phase-Transfer Catalytic Alkylation of 2-Phenyl-2-imidazoline-4-carboxylic Acid tert-Butyl Esters.

Yohan Park, Sukhoon Kang, Young Ju Lee, Taek-Soo Kim, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2010

File:

PDF, 28 KB

2010

31

ChemInform Abstract: Cinchona-Based Phase-Transfer Catalysts for Asymmetric Synthesis

Sang-sup Jew, Hyeung-geun Park

Journal:

Year:

2010

File:

PDF, 15 KB

2010

32

ChemInform Abstract: Novel Cinchona-Aminobenzimidazole Bifunctional Organocatalysts.

Lei Zhang, Myoung-Mo Lee, Soo-Mi Lee, Jihye Lee, Maosheng Cheng, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2010

File:

PDF, 40 KB

2010

33

ChemInform Abstract: Cinchona-Catalyzed Nucleophilic α-Substitution of Carbonyl Derivatives

Hyeung-geun Park, Byeong-Seon Jeong

Journal:

Year:

2010

File:

PDF, 19 KB

2010

34

ChemInform Abstract: Synthesis of (-)-Paroxetine via Enantioselective Phase-Transfer Catalytic Monoalkylation of Malonamide Ester.

Mi-hyun Kim, Yohan Park, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2010

File:

PDF, 35 KB

2010

35

ChemInform Abstract: Synthesis of (αR,βS)-Epoxyketones by Asymmetric Epoxidation of Chalcones with Cinchona Phase-Transfer Catalysts.

Mi-Sook Yoo, Dong-Guk Kim, Min Woo Ha, Sang-sup Jew, Hyeung-geun Park, Byeong-Seon Jeong

Journal:

Year:

2011

File:

PDF, 40 KB

2011

36

ChemInform Abstract: Cinchona-Derived Ammonium Salt Catalyzed Aza Diels—Alder Reaction of Danishefsky′s Diene with Imines.

Yohan Park, Eunyoung Park, Hyojun Jung, Yeon-Ju Lee, Sang-sup Jew, Hyeung-geun Park

Journal:

Year:

2011

File:

PDF, 38 KB

2011

37

ChemInform Abstract: Highly Enantioselective Synthesis of α,α-Dialkylmalonates by Phase-Transfer Catalytic Desymmetrization.

Suckchang Hong, Jihye Lee, Minsik Kim, Yohan Park, Cheonhyoung Park, Mi-hyun Kim, Sang-sup Jew, Hyeung-geun Park

Journal:

Year:

2011

File:

PDF, 37 KB

2011

38

Solvent Effects in the Enantioselective Catalytic-Phase-Transfer Alkylation of Polymer-Supported Glycine–Imine tert-Butyl Ester: Asymmetric Solid-Phase Synthesis of (R)-α-Amino Acid Derivatives

Mi-Jeong Kim, Sang-sup Jew, Hyeung-geun Park, Byeong-Seon Jeong

Journal:

European Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 164 KB

english, 2007

39

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

Fu-Nan Li, Nam-Jung Kim, Seung-Mann Paek, Do-Yeon Kwon, Kyung Hoon Min, Yeon-Su Jeong, Sun-Young Kim, Young-Ho Park, Hee-Doo Kim, Hyeung-Geun Park, Young-Ger Suh

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 725 KB

english, 2009

40

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists

Fu-Nan Li, Nam-Jung Kim, Dong-Jo Chang, Jaebong Jang, Hannah Jang, Jong-Wha Jung, Kyung-Hoon Min, Yeon-Su Jeong, Sun-Young Kim, Young-Ho Park, Hee-Doo Kim, Hyeung-Geun Park, Young-Ger Suh

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

41

Silicon switch approach in TRPV1 antagonist MK-056 and its analogues

Minsun Chang, Seol-Rin Park, Juhyun Kim, Mijung Jang, Jeong Hyun Park, Ji Eun Park, Hyeung-Geun Park, Young-Ger Suh, Yeon Su Jeong, Young-Ho Park, Hee-Doo Kim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 248 KB

english, 2010

42

N-4-Substituted-benzyl-N′-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity

Hyeung-geun Park, Ji-yeon Choi, Sea-hoon Choi, Mi-kyung Park, Jihye Lee, Young-ger Suh, Hawon Cho, Uhtaek Oh, Jiyoun Lee, Sang-Uk Kang, Jeewoo Lee, Hee-Doo Kim, Young-Ho Park, Yeon Su Jeong, Jin Kyu C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 208 KB

english, 2004

43

N-4-Methansulfonamidobenzyl-N′-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands

Hyeung-geun Park, Ji-yeon Choi, Sea-hoon Choi, Mi-kyung Park, Jihye Lee, Young-Ger Suh, Hawon Cho, Uhtaek Oh, Hee-Doo Kim, Yung Hyup Joo, Sun-Young Kim, Young-Ho Park, Yeon Su Jeong, Jin Kyu Choi, Jin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 181 KB

english, 2004

44

Polymeric chiral phase-transfer catalysts derived from cinchona alkaloids for enantioselective synthesis of α-amino acids

Jeong-Hee Lee, Mi-Sook Yoo, Ji-Hee Jung, Sang-sup Jew, Hyeung-geun Park, Byeong-Seon Jeong

Journal:

Year:

2007

Language:

english

File:

PDF, 605 KB

english, 2007

45

Asymmetric synthesis of α,β-epoxysulfones via phase-transfer catalytic Darzens reaction

Jin-Mo Ku, Mi-Sook Yoo, Hyeung-geun Park, Sang-sup Jew, Byeong-Seon Jeong

Journal:

Year:

2007

Language:

english

File:

PDF, 222 KB

english, 2007

46

Solid-phase synthesis of α-alkylserines via phase-transfer catalytic alkylation of polymer-supported 2-phenyl-2-oxazoline-4-carboxylate

Jihye Lee, Min Woo Ha, Taek-Soo Kim, Mi-Jeong Kim, Jin-Mo Ku, Sang-sup Jew, Hyeung-geun Park, Byeong-Seon Jeong

Journal:

Year:

2009

Language:

english

File:

PDF, 507 KB

english, 2009

47

Enantioselective synthesis of (S)-4-methyleneglutamic acid via tandem conjugate addition–elimination under phase-transfer catalytic conditions

Sukhoon Kang, Qinghua Shi, Min Woo Ha, Jin-Mo Ku, Maosheng Cheng, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Year:

2010

Language:

english

File:

PDF, 230 KB

english, 2010

48

Cinchona-derived ammonium salts-catalyzed aza Diels–Alder reaction of Danishefsky’s diene with imines

Yohan Park, Eunyoung Park, Hyojun Jung, Yeon-Ju Lee, Sang-sup Jew, Hyeung-geun Park

Journal:

Year:

2011

Language:

english

File:

PDF, 256 KB

english, 2011

49

Solid-phase synthetic method for (±)-α-amino acids via phase-transfer catalytic alkylation

Hyeung-geun Park, Mi-Jeong Kim, Mi-Kyung Park, Hyun-Ju Jung, Jihye Lee, Yeon-Ju Lee, Byeong-Seon Jeong, Jeong-Hee Lee, Mi-Sook Yoo, Jin-Mo Ku, Sang-sup Jew

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

50

Highly efficient polymer supported phase-transfer catalysts containing hydrogen bond inducing functional groups

Qinghua Shi, Yeon-Ju Lee, Mi-Jeong Kim, Mi-Kyung Park, Kyoungyim Lee, Hongrui Song, Maosheng Cheng, Byeong-Seon Jeong, Hyeung-geun Park, Sang-sup Jew

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 361 KB

english, 2008